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Biolog

Biolog is a world leader in cell-based phenotypic testing technologies and assays. Biolog has focused efforts on developing technologies and products to test properties of cells (phenotypes) very simply and efficiently.

The company's product lines have been built upon patented technology that greatly simplifies testing of cells. Biolog's first products were introduced in 1988 and by 1990 it had established a profitable growing business in microbiology for the identification and characterization of microbial cells.

Biolog is the only company providing technology to identify a very wide range and large number of microbial species (> 2,900) by simple phenotypic testing. Their products, marketed under the MicroLog™, MicroStation™ and OmniLog® brand names, are sold worldwide.

Principal customers of the identification products are laboratories needing state-of-the-art capabilities, especially pharmaceutical, biotech, cosmetics, and medical device companies, university and government research laboratories.

Biolog’s revolutionary Phenotype MicroArray™ technology allows researchers to evaluate thousands of cellular phenotypes simultaneously in both microbial and mammalian cells. Development of array sets testing nearly 2,000 phenotypes of microbial cells was completed and first introduced in 2001. Further work has subsequently resulted in array sets testing nearly 1,500 phenotypes of mammalian cells. These arrays are being used in a wide range of R&D applications including basic research in cancer, metabolic and mitochondrial disorders, nutrition, toxicology, drug discovery, and bioprocess development.

Bacteria, Yeast and Fungi Identification

The Biolog Microbial ID System can rapidly identify over 2,900 species of aerobic and anaerobic bacteria, yeasts and fungi. These easy to use systems provide reference laboratory quality identifications. Biolog Systems do this without the labor-intensive requirements of conventional strips or panels. There is a Biolog System for any size laboratory, from full and semi-automatic to manually read systems.

Microbial Detection using Chromogenic Media

Rainbow® Agars offer a simple selective and chromogenic medium to help you conveniently detect strains of E.coli O157, Salmonella, Shigella and Aeromonas with results in less than 24 hours. Rainbow Agar O157 has both selective and chromogenic properties that make it particularly useful for isolating pathogenic E.coli strains. Rainbow Agar Salmonella utilizes an enhanced detection chemistry to determine H2S production among Salmonella spp. Rainbow Agar Shigella/Aeromonas was developed to directly isolate these important causative agents of gastroenteritis.

Microbial Community Analysis with EcoPlates™

Microbial communities provide useful information about environmental change. Microorganisms are present in virtually all environments and are typically the first organisms to react to chemical and physical changes in the environment. Changes in microbial communities are often a precursor to changes in the health and viability of the environment as a whole.

Mitochondrial Function Assays with MitoPlates™

Mitochondria can be interrogated and characterized in novel ways, looking at rates of substrate metabolism, sensitivity to drugs and other chemicals, and effects of mutations in mitochondria-related genes.

Phenotype MicroArrays for Mammalian Cells (PM-M)

PMM assays are cell-based assays provided in five categories and used to determine up to 1,400 metabolic and chemical sensitivity phenotypes of mammalian cells. They use 96 well plates pre-loaded with carbon-energy and nitrogen substrates, ions, hormones/cytokines and anti-cancer agents. Cells of interest are scanned for phenotypes by adding 50 ul of a cell suspension (in IF-M1 or IF-M2 media) to each well followed by the addition of 10 ul of Biolog's proprietary redox (MA or MB) dye.