Phenotype MicroArrays for Mammalian Cells 

Phenotype MicroArray Mammalian assays are cell-based assays used to investigate up to 1,400 metabolic and chemical sensitivity phenotypes of mammalian cells. They use 96 well plates pre-loaded with carbon-energy and nitrogen substrates, ions, hormones/cytokines and anti-cancer agents. Plates are inoculated with the cells of interest and Biolog’s proprietary redox dye. In some wells, the cells are stimulated and in other wells inhibited. The generation of energy-rich NADH by the cells reduces the redox dye and brings about a color change which is then read with Biolog’s OmniLog automated incubator-reader.

Phenotype MicroArray Mammalian Assays can be used for diverse research and applications including:
  • Correlating genotypes with phenotypes
  • Studying metabolic reprogramming in cancer and anti-cancer drug sensitivity
  • Drug discovery research and toxicity screening
  • Cell line and bioprocess improvement
  • Cellular metabolism, metabolic disorders, nutrition
  • Drug discovery Cell energetics, growth and death and toxicity screening
  • Cell line QC and authentication