Phenotype MicroArrays for Microbial Cells

Phenotype MicroArrays (PMs) represent the third major technology, alongside DNA Microarrays and Proteomic Technologies, that is needed in the genomic era of research and drug development. Just as DNA Microarrays and Proteomic Technologies have made it possible to assay the level of thousands of genes or proteins all at once, Phenotype MicroArrays make it possible to quantitatively measure thousands of cellular phenotypes all at once.

Phenotype MicroArray technology enables researchers to evaluate nearly 2000 phenotypes of a microbial cell in a single experiment. Through comprehensive and precise quantitation of phenotypes, researchers are able to obtain an unbiased perspective of the effect on cells of genetic differences, environmental change, and exposure to drugs and chemicals.
You can:

  • Correlate genotypes with phenotypes
  • Determine a cell’s metabolic and chemical sensitivity properties
  • Discover new targets for antimicrobial compounds
  • Optimize cell lines and culture conditions in bioprocess development
  • Characterize cell phenotypes for taxonomic or epidemiological studies

Phenotype MicroArrays are preconfigured 96 well plates containing different classes of chemical compounds designed to test for the presence or absence of specific cellular phenotypes. There are 10 panels designed to interrogate metabolic pathways along with ionic, osmotic and pH effects, and 10 panels to assess the sensitivity to various antimicrobials with different mechanisms of action.